GHK-Cu Copper
Proper Handling
- Reconstitute with 3 mL Bacteriostatic Water
- Specifications: Lyophilized powder in 3 mL vial. Purity (>99%) meets or exceeds U.S. Pharmacopeia (USP) regulations.
- Storage: In lyophilized form, the peptide is stable for 3 years. Protect from light. Refrigerate and use within 4-6 weeks after opening or reconstituting.
GHK-Cu (Glycyl-L-Histidyl-L-Lysine-Copper) is a naturally occurring copper peptide found in the human body. It is composed of three amino acids bound to a copper ion and is known for its regenerative properties. GHK-Cu plays a significant role in wound healing, tissue repair, reducing inflammation, and reversing signs of aging. Growing in popularity is the Glow Peptide Protocol, which combines BPC-157/TB-500 and GHK-Cu for skin rejuvenation and anti-aging benefits. This blend promotes collagen synthesis, improves wound healing, reduces inflammation, and helps regenerate tissue, giving the skin a more youthful appearance.
Science-Backed Research
- Promotes Collagen Production
- Accelerates Wound Healing
- Reduces Inflammation
- Stimulates Hair Growth
- Enhances Skin Regeneration
- Provides Antioxidant Protection
- Improves Skin Barrier Function
- Supports Copper Transport
CAS Number 49557-75-7
PubChem CID 342538
Molecular Weight 340.38 g/mol
Molecular Formula C14H24N6O4
Synonyms Copper Peptide, GHK CU, GHK-Copper
Storage (Lyophilized)
At 39 Fahrenheit: 2 years
At -4 Fahrenheit: 3 years
The products sold on this website are intended for research use only, unless prescribed by a licensed physician or you received authorization under the Right to Try Act Public Law No: 115-176. Always consult with a healthcare provider or medical professional before starting any treatment. Please refer to our terms and conditions prior to purchase.
This product comes in the form of lyophilized powder and must be reconstituted with bacteriostatic water prior to use.
Safety Information: Keep this product out of the reach of children. This product may have limited research available about it and may result in adverse effects if improperly handled. This product is not a dietary supplement, but a pure substance, sold as a raw product. We attest exclusively to the quality, purity and description of the products we provide. This product is for use and handling only by persons with the knowledge and equipment to safely handle this product. You agree to indemnify us for any adverse effects that may arise from improper handling of this product.
The articles and information on products that may be found on this website are provided exclusively for the purposes of providing information and education. The Food and Drug Administration has not reviewed these products or given permission for the treatment or prevention of any disease, medical condition, or ailment using them.
- Pickart, Loren, and Anna Margolina. “Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data.” International journal of molecular sciences vol. 19,7 1987. 7 Jul. 2018, doi:10.3390/ijms19071987. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073405/
- Pickart L, Freedman JH, Loker WJ, Peisach J, Perkins CM, Stenkamp RE, Weinstein B. Growth-modulating plasma tripeptide may function by facilitating copper uptake into cells. Nature. 1980 Dec 25;288(5792):715-7. doi: 10.1038/288715a0. PMID: 7453802. https://pubmed.ncbi.nlm.nih.gov/7453802/
- L.O. Pilgeram, L.R. Pickart, Control of fibrinogen biosynthesis: The role of free fatty acid, Journal of Atherosclerosis Research, Volume 8, Issue 1, 1968, Pages 155-166, ISSN 0368-1319, https://doi.org/10.1016/S0368-1319(68)80089-4
- Pickart L, Freedman JH, Loker WJ, Peisach J, Perkins CM, Stenkamp RE, Weinstein B. Growth-modulating plasma tripeptide may function by facilitating copper uptake into cells. Nature. 1980 Dec 25;288(5792):715-7. doi: 10.1038/288715a0. PMID: 7453802. https://pubmed.ncbi.nlm.nih.gov/7453802/
- Pickart L, Vasquez-Soltero JM, Margolina A. GHK and DNA: resetting the human genome to health. Biomed Res Int. 2014;2014:151479. doi: 10.1155/2014/151479. Epub 2014 Sep 11. PMID: 25302294; PMCID: PMC4180391. https://pubmed.ncbi.nlm.nih.gov/25302294/
- Maquart FX, Pickart L, Laurent M, Gillery P, Monboisse JC, Borel JP. Stimulation of collagen synthesis in fibroblast cultures by the tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu2+. FEBS Lett. 1988 Oct 10;238(2):343-6. doi: 10.1016/0014-5793(88)80509-x. PMID: 3169264. https://pubmed.ncbi.nlm.nih.gov/3169264/
- Siméon A, Emonard H, Hornebeck W, Maquart FX. The tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu2+ stimulates matrix metalloproteinase-2 expression by fibroblast cultures. Life Sci. 2000 Sep 22;67(18):2257-65. doi: 10.1016/s0024-3205(00)00803-1. PMID: 11045606. https://pubmed.ncbi.nlm.nih.gov/11045606/
- Cangul IT, Gul NY, Topal A, Yilmaz R. Evaluation of the effects of topical tripeptide-copper complex and zinc oxide on open-wound healing in rabbits. Vet Dermatol. 2006 Dec;17(6):417-23. doi: 10.1111/j.1365-3164.2006.00551.x. PMID: 17083573. https://pubmed.ncbi.nlm.nih.gov/17083573/
- Gul NY, Topal A, Cangul IT, Yanik K. The effects of topical tripeptide copper complex and helium-neon laser on wound healing in rabbits. Vet Dermatol. 2008 Feb;19(1):7-14. doi: 10.1111/j.1365-3164.2007.00647.x. PMID: 18177285. https://pubmed.ncbi.nlm.nih.gov/18177285/
- Mulder GD, Patt LM, Sanders L, Rosenstock J, Altman MI, Hanley ME, Duncan GW. Enhanced healing of ulcers in patients with diabetes by topical treatment with glycyl-l-histidyl-l-lysine copper. Wound Repair Regen. 1994 Oct;2(4):259-69. doi: 10.1046/j.1524-475X.1994.20406.x. PMID: 17147644. https://pubmed.ncbi.nlm.nih.gov/17147644/
- Bobyntsev II, Chernysheva OI, Dolgintsev ME, Smakhtin MY, Belykh AE. Anxiolytic effects of Gly-His-Lys peptide and its analogs. Bull Exp Biol Med. 2015 Apr;158(6):726-8. doi: 10.1007/s10517-015-2847-3. Epub 2015 Apr 23. PMID: 25900608. https://pubmed.ncbi.nlm.nih.gov/25900608/
- Sever'yanova LА, Dolgintsev ME. Effects of Tripeptide Gly-His-Lys in Pain-Induced Aggressive-Defensive Behavior in Rats. Bull Exp Biol Med. 2017 Dec;164(2):140-143. doi: 10.1007/s10517-017-3943-3. Epub 2017 Nov 27. PMID: 29181666. https://pubmed.ncbi.nlm.nih.gov/29181666/
Frequently Asked Questions
GHK-Cu Copper
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GHK-Cu (Glycyl-L-histidyl-L-lysine-Copper) is a copper peptide complex naturally occurring in the human body. It plays a crucial role in wound healing, skin repair, inflammation control, and overall tissue regeneration. GHK-Cu has been studied extensively for its regenerative and anti-aging properties, particularly in skin and hair care, but its benefits extend to various areas of health.
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Wound Healing and Skin Repair: GHK-Cu promotes collagen production and assists in tissue remodeling, making it effective for healing wounds, reducing scars, and improving skin elasticity and firmness.
Anti-Inflammatory Properties: It can reduce inflammation and oxidative stress, which contributes to healthier skin and overall healing.
Anti-Aging Effects: By stimulating collagen production and increasing skin’s structural proteins, GHK-Cu helps reduce the appearance of fine lines, wrinkles, and hyperpigmentation.
Hair Growth: GHK-Cu has been shown to stimulate hair growth by increasing hair follicle size and reducing hair thinning.
Antioxidant Properties: The peptide acts as a powerful antioxidant, protecting cells from oxidative damage.
Tissue Regeneration: It assists in the regeneration of various tissues, including lungs and liver, due to its ability to modulate gene expression related to tissue repair.
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GHK-Cu Copper can be injected subcutaneously (under the skin) for systemic benefits, such as improving tissue repair, reducing inflammation, or promoting overall skin health. This method is commonly used in medical settings.
GHK-Cu Copper is for research purposes only, unless prescribed by a licensed physician.
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Blending GHK-Cu with BPC-157 can make the injection less painful. BPC-157 has anti-inflammatory and healing properties, which can help reduce irritation or discomfort that sometimes occurs with peptide injections. This combination helps improve tissue repair while minimizing any potential injection site pain or sensitivity.
While GHK-Cu is generally well-tolerated, some potential side effects include:
- Injection site reactions: Redness, itching, or mild discomfort at the injection site.
- Allergic reactions: Though rare, some may experience allergic responses such as swelling, rash, or hives.
- Temporary skin discoloration: In some cases, it may cause mild, temporary blue or green skin tint due to the copper content.
- Systemic effects: Rarely, it may lead to headaches, dizziness, or nausea.
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We're happy to help answer questions you may have, or refer you to a licensed healthcare professional. Email us at care@somapeptides.com or schedule a consult.
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Speak with specialists in peptide therapy about reconstituting lyophilized peptides, proper handling and storage, and other questions you may have.