CJC-1295 w/ DAC
Proper Handling
- Reconstitute with Bacteriostatic Water
- Specifications: Lyophilized powder in 3 mL vial. Purity (>99%) meets or exceeds U.S. Pharmacopeia (USP) regulations.
- Storage: In lyophilized form, the peptide is stable for 3 years. Protect from light. Refrigerate and use within 4-6 weeks after opening or reconstituting.
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CJC-1295 is a synthetic GHRH (growth hormone releasing hormone) analogue made up of 30 amino acids. It has been found to be highly effective with regards to the increase of growth hormone secretion and IGF-1 without negatively affecting GH secretion. CJC-1295 also promotes slow wave deep sleep, which is responsible for the highest level of muscle growth and memory retention and rejuvenation.
CJC-1295 is often combined with Ipamorelin due to its enhanced specificity as a GHRH. This peptide generates similar increases in growth hormone secretion, but without the appetite stimulation.
Science-Backed Research
- Increase in muscle mass
- Promotes slow wave deep sleep
- Strengthens immune system
- Improves recovery time and repair from injuries
- Better cognitive function and mental clarity
- Improves skin elasticity, reduces wrinkles, and strengthens nails and hair
- Increase in metabolic rate and energy
- Increases fat loss
Storage (Lyophilized)
- Short Term: Room Temperature 4-8 Weeks
- Long Term: Refrigerated (Under 39 Fahrenheit) 1-2 years
Frozen (Under -4 Fahrenheit) 3 years
Storage (Reconstituted)
- After mixed with bacteriostatic water, peptide solutions must be refrigerated and used within 4-6 weeks.
CAS Number 446262-90-4
PubChem CID 91976842
Molecular Weight 3367.9 g/mol
Molecular Formula C152H252N44O42
This product is sold as a pure compound for research purposes only. This product comes in the form of lyophilized powder and must be reconstituted with bacteriostatic water prior to use. Please refer to our terms and conditions prior to purchase.
Safety Information: Keep this product out of the reach of children. This material has limited research available about it and may result in adverse effects if improperly handled or consumed. This product is not a dietary supplement, but a pure substance, sold as a raw material. We attest exclusively to the quality, purity and description of the materials we provide. This product is for use and handling only by persons with the knowledge and equipment to safely handle this material. You agree to indemnify us for any adverse effects that may arise from improper handling and/or consumption of this product.
The articles and information on products that may be found on this website are provided exclusively for the purposes of providing information and education. These items are not pharmaceuticals or medications, and the Food and Drug Administration has not given permission for the treatment or prevention of any disease, medical condition, or ailment using them.
- Linder J. The science behind peptides. Plast Surg Nurs. 2012 Apr-Jun;32(2):71-2. doi: 10.1097/PSN.0b013e3182577344. PMID: 22647954.
- Henninge J, Pepaj M, Hullstein I, Hemmersbach P. Identification of CJC-1295, a growth-hormone-releasing peptide, in an unknown pharmaceutical preparation. Drug Testing and Analysis. 2010 Nov-Dec;2(11-12):647-650. DOI: 10.1002/dta.233.
- Kastin, A., 2006. Handbook of biologically active peptides. 1st ed. Amsterdam: Academic Press, CHAPTER 93 - Growth Hormone-Releasing Hormone pp.663-671.
- Vivo.colostate.edu. 2021. Growth Hormone (Somatotropin). (online) Available at: (Accessed 26 April 2021).
- Steiger A, Holsboer F. Neuropeptides and human sleep. Sleep. 1997 Nov;20(11):1038-52. PMID: 9456470.
- ClinicalTrials.gov, A service of the US National Institutes of Health. Available at: http://clinicaltrials.gov/ct2/show/NCT00267527 (27 June 2010).
- Teichman SL, Neale A, Lawrence B, Gagnon C, Castaigne JP, Frohman LA. Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, in healthy adults. J Clin Endocrinol Metab. 2006 Mar;91(3):799-805. doi: 10.1210/jc.2005-1536. Epub 2005 Dec 13. PMID: 16352683.
- Ionescu M, Frohman LA. Pulsatile secretion of growth hormone (GH) persists during continuous stimulation by CJC-1295, a long-acting GH-releasing hormone analog. J Clin Endocrinol Metab. 2006 Dec;91(12):4792-7. doi: 10.1210/jc.2006-1702. Epub 2006 Oct 3. PMID: 17018654.
- Alba M, Fintini D, Sagazio A, Lawrence B, Castaigne JP, Frohman LA, Salvatori R. Once-daily administration of CJC-1295, a long-acting growth hormone-releasing hormone (GHRH) analog, normalizes growth in the GHRH knockout mouse. Am J Physiol Endocrinol Metab. 2006 Dec;291(6):E1290-4. doi: 10.1152/ajpendo.00201.2006. Epub 2006 Jul 5. PMID: 16822960.
- Van Hout MC, Hearne E. Netnography of Female Use of the Synthetic Growth Hormone CJC-1295: Pulses and Potions. Subst Use Misuse. 2016 Jan 2;51(1):73-84. doi: 10.3109/10826084.2015.1082595. Epub 2016 Jan 15. PMID: 26771670.
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Frequently Asked Questions
CJC-1295 w/ DAC
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CJC-1295 with DAC is a synthetic peptide analog of growth hormone-releasing hormone (GHRH). The key feature of this version of CJC-1295 is the inclusion of the Drug Affinity Complex (DAC), which significantly extends its half-life in the body. This allows the peptide to provide a more sustained increase in growth hormone (GH) levels over a prolonged period.
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The primary difference between CJC-1295 with DAC and CJC-1295 without DAC lies in the peptide's half-life and duration of action, which is influenced by the presence or absence of the Drug Affinity Complex (DAC).
Duration of Action: With DAC has a long-lasting effect (up to 8 days), while without DAC has a much shorter duration (hours).
Frequency: With DAC requires less frequent use (once or twice a week), while NO DAC requires more frequent use (multiple times a week).
Mechanism: With DAC offers sustained, long-term GH release, while NO DAC provides short, pulsatile GH release.
Application: With DAC is often used for long-term therapies like anti-aging, while NO DAC is used in settings where short-term, controlled GH pulses are desired.
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Sustained Growth Hormone Release
Extended Half-Life: Thanks to the DAC, CJC-1295 can remain active in the body for up to 8 days, providing a prolonged stimulation of the pituitary gland to release GH.
Consistent IGF-1 Levels: The extended release of GH also leads to a more sustained increase in Insulin-Like Growth Factor 1 (IGF-1), which is important for growth, development, and metabolic processes.
Anti-Aging and Longevity
Reduction in Aging Symptoms: The consistent release of GH helps improve skin elasticity, reduce wrinkles, and support overall tissue health, contributing to a more youthful appearance.
Improved Sleep Patterns: Patients often report better sleep quality, which is essential for recovery, cognitive function, and overall well-being. Enhanced GH levels, particularly during deep sleep, contribute to this effect.
Muscle Growth and Fat Loss
Increased Muscle Mass: By promoting higher levels of GH and IGF-1, CJC-1295 with DAC aids in the development of lean muscle mass, making it beneficial for those looking to improve their body composition.
Enhanced Fat Metabolism: The peptide promotes lipolysis, the breakdown of fat cells, which helps reduce body fat and improve overall metabolic health.
Recovery and Healing
Accelerated Recovery: The peptide supports faster recovery from injuries, surgeries, or intense physical activity by promoting tissue repair and regeneration.
Bone and Joint Health: GH and IGF-1 are crucial for maintaining bone density and joint integrity, which can be particularly beneficial for aging individuals or those with joint issues.
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Clinical Applications
Age Management Therapy: CJC-1295 with DAC is commonly used in anti-aging protocols to help patients maintain youthful levels of GH, which can improve vitality, skin health, and overall quality of life.
Sports Medicine and Rehabilitation: The peptide is valuable for patients recovering from injuries or surgeries, as well as athletes looking to enhance muscle growth and recovery times.
Metabolic Health: CJC-1295 with DAC can be an effective tool in weight management programs, especially for patients struggling with stubborn fat or metabolic disorders.
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Some users may experience mild side effects such as:
- Injection site reactions (redness or swelling)
- Water retention
- Headaches
- Nausea
- Rarely, there can be an increase in cortisol levels or blood sugar levels
Remember, everyone reacts differently to substances like CJC-1295 w/ DAC due to individual physiological differences such as metabolism rate and overall health status. Consult with a licensed healthcare professional if you are considering peptide therapy.
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Cancer or Tumor History
Growth Promotion: Due to its ability to stimulate growth hormone release, CJC-1295 with DAC may not be suitable for individuals with active cancer or a history of cancer, particularly those with hormone-sensitive tumors.
Diabetes
Blood Sugar Management: The peptide can influence blood sugar levels, so it should be used with caution in individuals with diabetes or those on glucose-lowering medications. Close monitoring is required.
Acute or Chronic Illness
Illness Impact: Patients with severe acute or chronic illnesses, particularly those affecting the liver or kidneys, should use CJC-1295 with DAC cautiously, as it could impact the body’s metabolism.
Hypersensitivity
Allergic Reactions: Patients with known hypersensitivity to any component of the peptide formulation should not use CJC-1295 with DAC.
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CJC-1295 w/ DAC is an injectable peptide administered subcutaneously through the fat. The most fatty parts of the body are the abdomen, side or back of upper arms, and front of thighs.
CJC-1295 w/ DAC is for research purposes only, unless prescribed by a licensed physician.
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We're happy to help answer questions you may have, or refer you to a licensed healthcare professional for medical advice. Email us at care@somapeptides.com or schedule a telehealth appointment.
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